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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HIRA
All Species:
43.03
Human Site:
S335
Identified Species:
59.17
UniProt:
P54198
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54198
NP_003316.3
1017
111835
S335
D
K
S
I
M
D
I
S
W
T
L
N
G
L
G
Chimpanzee
Pan troglodytes
XP_001165585
1017
111787
S335
D
K
S
I
M
D
I
S
W
T
L
N
G
L
G
Rhesus Macaque
Macaca mulatta
XP_001112873
1138
124408
W456
K
S
I
M
D
I
S
W
T
L
N
G
L
G
I
Dog
Lupus familis
XP_543550
1017
111618
S335
D
K
S
I
M
D
I
S
W
T
L
N
G
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q61666
1015
111748
S335
D
K
S
I
M
D
I
S
W
T
L
N
G
L
G
Rat
Rattus norvegicus
NP_001129232
1015
111665
S335
D
K
S
I
M
D
I
S
W
T
L
N
G
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P79987
1019
112055
S335
D
K
S
I
M
D
I
S
W
T
L
N
G
L
G
Frog
Xenopus laevis
Q8QFR2
1013
112021
S335
D
K
S
I
M
D
I
S
W
T
L
N
G
L
G
Zebra Danio
Brachydanio rerio
XP_696478
1010
111223
T335
D
K
S
I
M
D
I
T
W
T
L
N
G
L
G
Tiger Blowfish
Takifugu rubipres
O42611
1025
111838
S335
D
K
S
I
M
D
I
S
W
T
L
T
G
L
G
Fruit Fly
Dros. melanogaster
O17468
1047
113397
T332
N
A
S
I
L
D
L
T
W
G
P
Q
E
C
L
Honey Bee
Apis mellifera
XP_001122939
838
91355
V181
K
G
I
T
W
D
P
V
G
K
Y
L
A
S
Q
Nematode Worm
Caenorhab. elegans
Q09589
935
103412
A278
K
G
T
T
C
V
R
A
M
P
R
L
I
E
A
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Q32SG6
964
105548
N307
T
K
E
Q
Q
P
Y
N
V
I
A
I
G
S
Q
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LXN4
1051
115544
S335
G
Q
S
V
V
D
L
S
W
S
P
D
G
Y
S
Baker's Yeast
Sacchar. cerevisiae
P32479
840
93871
K183
D
V
H
Q
S
L
V
K
G
V
V
F
D
P
A
Red Bread Mold
Neurospora crassa
Q7RZI0
1035
112420
S333
T
I
W
N
T
N
T
S
R
P
V
L
I
V
Q
Conservation
Percent
Protein Identity:
100
99.9
88.4
96.5
N.A.
95.7
95.5
N.A.
N.A.
86
78
69.8
67.7
31.1
40
26.5
N.A.
Protein Similarity:
100
99.9
88.9
98
N.A.
97.5
97.7
N.A.
N.A.
93.1
88.5
83.2
81.3
48
55.1
46.1
N.A.
P-Site Identity:
100
100
0
100
N.A.
100
100
N.A.
N.A.
100
100
93.3
93.3
26.6
6.6
0
N.A.
P-Site Similarity:
100
100
6.6
100
N.A.
100
100
N.A.
N.A.
100
100
100
93.3
53.3
6.6
13.3
N.A.
Percent
Protein Identity:
N.A.
25.6
N.A.
25
22.4
25.9
Protein Similarity:
N.A.
43.7
N.A.
43.3
41.2
45.8
P-Site Identity:
N.A.
13.3
N.A.
33.3
6.6
6.6
P-Site Similarity:
N.A.
20
N.A.
73.3
20
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
0
6
0
0
6
0
6
0
12
% A
% Cys:
0
0
0
0
6
0
0
0
0
0
0
0
0
6
0
% C
% Asp:
59
0
0
0
6
71
0
0
0
0
0
6
6
0
0
% D
% Glu:
0
0
6
0
0
0
0
0
0
0
0
0
6
6
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% F
% Gly:
6
12
0
0
0
0
0
0
12
6
0
6
65
6
53
% G
% His:
0
0
6
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
6
12
59
0
6
53
0
0
6
0
6
12
0
6
% I
% Lys:
18
59
0
0
0
0
0
6
0
6
0
0
0
0
0
% K
% Leu:
0
0
0
0
6
6
12
0
0
6
53
18
6
53
6
% L
% Met:
0
0
0
6
53
0
0
0
6
0
0
0
0
0
0
% M
% Asn:
6
0
0
6
0
6
0
6
0
0
6
48
0
0
0
% N
% Pro:
0
0
0
0
0
6
6
0
0
12
12
0
0
6
0
% P
% Gln:
0
6
0
12
6
0
0
0
0
0
0
6
0
0
18
% Q
% Arg:
0
0
0
0
0
0
6
0
6
0
6
0
0
0
0
% R
% Ser:
0
6
65
0
6
0
6
59
0
6
0
0
0
12
6
% S
% Thr:
12
0
6
12
6
0
6
12
6
53
0
6
0
0
0
% T
% Val:
0
6
0
6
6
6
6
6
6
6
12
0
0
6
0
% V
% Trp:
0
0
6
0
6
0
0
6
65
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
6
0
0
0
6
0
0
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _